Found 36 matching trials
The Role of Endothelin-1 in Sickle Cell Disease
PHASE1The primary goal of the study is to determine the safety and tolerability o...
Location
Augusta University
Efficacy of Ambrisentan in Limited Scleroderma Patients in Improving Blood Flow to Hands or Feet
NAThe purpose of this study is to investigate the effectiveness of a drug cal...
Location
Nilanjana Bose, Md
A Long Term Study of Ambrisentan in Pulmonary Arterial Hypertension Subjects Having Completed AMB-320 (NCT00423748) or AMB-321 (NCT00423202)
PHASE3AMB-320/321-E was designed to provide long-term, controlled monitoring of p...
Location
Sanatorio Otamendi
Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH)
PHASE2Trial Design Patients with borderline PAH indicated by borderline mPAP valu...
Location
Thoraxclinic at the University of Heidelberg
Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
PHASE3It is hypothesised that ambrisentan may provide benefit to subjects with in...
Location
GSK Investigational Site
Ambrisentan for Early Low-Risk Pulmonary Arterial Hypertension
NAThis is an investigator-initiated, multicenter, randomized, double-blind, p...
Location
Multiple Locations
Efficacy and Safety of Combination Ambrisentan and Tadalafil in Patients With Portopulmonary Hypertension
PHASE4The purpose of this study is to evaluate the efficacy and safety of the com...
Location
Ochsner Clinic Foundation
The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy Volunteers
PHASE1This is a Phase I, three period, two sequence, open-label, randomized, cros...
Location
Duke Clinical Research Unit
Treatment With Ambrisentan in Patients With Borderline Pulmonary Arterial Hypertension
NAAn Investigator initiated trial (IIT) using a prospective, randomized, doub...
Location
Nanjing First Hospital
Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan
N/AThe aim of the present study is to assess the impact of CYP3A4-induction by...
Location
University Hospital Heidelberg